NFL, San Francisco 49ers and Cardinals
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49ers-Cardinals odds: Brock Purdy’s potential return has the Niners as slight road favorites
The Cardinals have the edge defensively, thanks to their pass rush, but a potential return of Brock Purdy and Ricky Pearsall, paired with an offensive line trending in the right direction, should mean the offense continues to hum. Mac Jones threw for 284 yards in Week 3. Pearsall was responsible for 117 of those.
The Niners' rookie class was forced into action early because of injuries, but has seen a significant drop in its contributions over the past month.
Niners Wire on MSN
Were any 49ers good in their dreary Week 10 loss to their blowout loss to the Rams?
Sunday was largely unkind to San Francisco. But, the 49ers had several standout performers in its loss versus the Los Angeles Rams.
Expert recap and game analysis of the Los Angeles Rams vs. San Francisco 49ers NFL game from November 9, 2025 on ESPN.
The San Francisco 49ers have a very unexpected quarterback controversy brewing in the Bay, as Mac Jones has filled in more than admirably while Brock Purdy has been sidelined with a toe injury.
Niners Wire on MSN
49ers PFF grades: Best and worst grades from Week 10 loss vs. Rams
The San Francisco 49ers fell to the Los Angeles Rams on Sunday. Here's who had the best and worst days, according to Pro Football Focus.
Following a successful first week of play with three wins to begin the 2025-26 season, the fifth-ranked LSU women’s basketball team returns t
Bosa was spotted by KPIX-TV reporter Matt Lively in the tunnel at Levi’s Stadium on Sunday, arriving to watch the 49ers eventually lose 42-26 to the Rams in an NFC West showdown. In the quick video clip, Bosa has a brace over his right knee as he walks to the team’s locker room.